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The Morpholino Group

We are a  group of crazy chemists and biologists passionate about nucleic acid therapeutics, specifically morpholino oligonucleotides. Meet the overexcited group below 👇

Meet Our Team

Meet the PI

Surajit Sinha, Ph.D.

Senior Professor,

School of Applied and Interdisciplinary Sciences,

Indian Association for the Cultivation of Science

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senjuti sen

Dr. Senjuti Sen

RA-I (TRC Project)

Development of Anticancer Therapeutics Using Morpholino Antisense.
NPDF, IICB, Kolkata
Ph.D. Bose Institute
M.Sc Calcutta University
B.Sc Calcutta University
Date of joining: July 2023

Shalini Gupta

Dr. Shalini Gupta

RA-I

An OCD patient with respect to cleanliness and organized things.

Synthesis of non-peptide-based delivery agents, ideally non-toxic, and their biological efficacy.

Ph.D. IACS, Kolkata
M.Sc. IACS (Int. Ph.D.)
B.Sc. Lady Brabourne College
Date of joining: June 2018

Abhishek Gupta

Dr. Abhishek Gupta
Ph.D. IACS, Kolkata

Four C’s of his life: Chemistry, Chicken, Carrom and Cricket (never plays though). Standardizes reactions slowly, steadily and with resilience.

Development of Azaproline-based peptides and delivery agents.
M. Sc. IACS (Int. Ph.D.)
B. Sc. Scottish Church College
Date of joining: June, 2018

Atanu Ghosh

Atanu Ghosh

Senior Research Fellow (CSIR)

Loves cricket. On the pitch, an all-rounder. Off the pitch, he loves to take clean NMR spectra.

Synthesis of Functionalized Morpholino Oligonucleotides.
M. Sc. IACS (Int. Ph.D.)
B. Sc. City College
Date of joining: July 2019

Arnab Das

Arnab Das

Senior Research Fellow (CSIR)

Mimicry artist of the group. DCM runs through his veins instead of blood.

Synthesis of Functionalized and Self-Transfecting Morpholino Oligonucleotides .
M. Sc. IACS (Int. Ph.D.)
B. Sc. Vivekananda College
Date of joining: July 2019

Swrajit Nath Sharma

Swrajit Nath Sharma

Senior Research Fellow

Focused, humble, and witty, with a keen interest in Chemistry and a passion for dancing.

Synthesis and evaluation of biological efficacy of IGT-ASO conjugates in Exon skipping models. 
M.Sc IACS (Int. Ph.D.)
Bsc. Dibrugarh University
Date of joining: September 2021

Sudipta Sarkar

Sudipta Sarkar

Senior Research Fellow (CSIR)

Serious Biologist. She isn't in any way shape or form what you think she is.

Oncoimmunotherapy
M.Sc, Rajabazar Science College, University of Calcutta
B.Sc.: Hooghly Mohsin College
Date of joining: February 2022

Md. Qasim

Md. Qasim

Senior Research Fellow (UGC)

Funny and serious. Calm and mischievous. He is not at all what you think he is.

Development of Internal Oligo-guanidinium Transporter (IGT).
M. Sc. IACS (Int. Ph.D.)
B. Sc. Maulana Azad College
Date of Joining: August 2022

Subhamoy Pratihar

Subhamoy Pratihar

Senior Research Fellow

Vivacious manager and go-to person of the group. Also a night owl and a comic.

Synthesis of Antisense Morpholino Oligonucleotides.
M.Sc. IACS (Int. Ph.D.)
B. Sc. Bankura Sammilani College.
Date of Joining: August 2022

Sharmeen Naaz

Sharmeen Naaz

Junior Research Fellow (UGC)

Therapeutic Evaluation of Antisense Oligonucleotide.
M.Sc & B.Sc Rammohan College
Date of Joining: August 2023

Debajyoti Kuilya

Debajyoti Kuilya

Junior Research Fellow

Calligrapher Gyani Baba, found his true calling in organic synthesis somewhere between chess and Marvel superheroes.

Synthesis of Antisense Morpholino oligonucleotides.
M.Sc. Vidyasagar University
B.Sc. Vidyasagar University
Date of joining: October 2023

Maria mukherjee

Maria Mukherjee

Junior Research Fellow (UGC)

​From oligonucleotide synthesis to in vitro cell biology to handling mice and financials, her unique skillset also includes singing and writing sentences inclined at 45 degrees.

Synthesis and evaluation of biological efficacy of Antisense Morpholino oligonucleotides.
M.Sc. University of Hyderabad
B.Sc. Jadavpur University
Date of joining: January 2024

saismm3072@iacs.res.in

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Alumni

Graduate students alumni:

1) Dr. Goutam Kumar Jana. Now at Pharma Co. ChemBiotek.

Thesis Title: Studies directed towards the synthesis of indolazepine-based alkaloid called "Ibogaine and its analogues".

2) Dr. Sankha Pattanayak. Senior Director of Chemistry, Creyo Bio, USA.

Thesis Title: 

3) Dr. Sibasish Paul. Postdoctoral Research Associate under Prof. Marvin H Caruther's group at the Department of Chemistry & Biochemistry, University of Colorado, Boulder, USA. now as a scientist in Agilent Technologies, Colorado, USA. 

Thesis Title: Synthesis and biological evaluation of alkaloids and modified nucleotides

4) Dr. Koushik Goswami. Post Doctoral Research Fellow under Dr. Stéphane P. Roche at the Department of Chemistry and Biochemistry, Florida Atlantic University. At present a guest Lecturer in Belur Ramkrishna Mission Vidyamandir and Research Associate by Kothari fellowship (UGC) in Kalyani University. At present Assistant professor in Amity University, Kolkata.

Thesis Title:

5) Dr. Amrita Chakraborty. Research Associate by Kothari fellowship (UGC) in Visva Bharati University, Santiniketan, W. B. and also a guest lecturer. At present Assistant Professor, A. N. College, Patna.

Thesis Title:

6) Dr. Indranil Duttagupta. Postdoctoral Research Associate under Prof. Gérard Audran in Aix-Marseille University, France. At present Durham University, UK.

Thesis Title: Synthesis and biological applications of artificial amino acids.

7) Dr. Bappaditya Nandi. Assistant Professor in Budge Budge Engineering College, Kolkata.

Thesis Title: Synthesis of modified morpholino nucleoside monomers, cationic oligomers and their cellular transfection studies.

8) Dr. Jhuma Bhadra. Postdoctoral fellow at Clemson University, USA (May 2017). At present March 1 st Boston College.

Thesis Title: 

9) Dr. Harleen Khatra. Assistant Professor, SUS College of Engineering.

Thesis Title: 

10) Dr. Keshab Chandra Ghosh. Now at IOCL.

Thesis Title: Synthesis of biologically important cyclic peptides non proteinogenic amino acids and peptides.

11) Dr. Isita Banerjee. Now at Chembiotek, Kolkata.

Thesis Title: Development of methodology for C-2 Arylation of Indoles and synthesis of Mercaptophenylalanines and their peptides.

12) Dr. Jayanta Kundu. Now at Alnylam Pharmaceuticals, USA.

Thesis Title: Design and synthesis of cellular transporter as a novel delivery vehicle for antisense oligonucleotides and towards the development of antisense therapy for the treatment of duchenne muscular dystrophy.

13) Dr. Chandra Bose. Now works as Assistant Editor, Wiley.

Thesis Title: Regulation of Hedgehog Signaling by Chemical Tools.

14) Dr. Ujjwal Ghosh. Research Scientist at GenELixir India Ltd, Visakhapatnam.

Thesis Title: Exploring PMOs from different perspectives: A novel synthesis strategy of 5’-thiol functionalization and incorporation of guanidinium groups in their delivery.

 

Research Associate Alumni:

1) Dr. Pragya P. Khan (DBT RA-1 for 3 years, Ph.D in Zoology, Visva Bharati University). At present working as a post doc Sunnyvale, California.

2) Dr. Priyanjalee Banerjee, (DBT RA-1), now Assisstant Professor, Raiganj Surendranath Mahavidyalaya, Raiganj. 

3) Dr. Ujjwal Das, (RA-1), now at Rutgers University, New Jersey, USA.

4) Dr. Pallab Shaw, (RA-1), now at University of Oklahoma (Health Stephenson Cancer Centre), USA.

 

Project Students Alumni (2019 and later):

 

1) Ms. Shreya Sinha (IntPhD, SAIS, project duration: July 2019-March 2020)

2) Mr. Abhishek Barua (IntPhD, SBS, project duration: June 2019-March 2020)

3) Ms. Shayari Bhattacharya (IntPhD, SAIS, project duration: June 2020-May 2021)

4) Ms. Firdaus Ahmed (IntPhD, SBS, project duration: June 2020-May 2021)

5) Mr. Swapnendu Deb (IntPhD, SAIS, project duration: September 2021-June 2022)

6) Ms. Neha Poddar (IntPhD, SAIS, project duration: September 2021-June 2022) 

7) Ms. Gargi Sarkar (IntPhD, SAIS, project duration: September 2022-May 2023)

8) Mr. Rohan Sharma (IntPhD, SAIS, project duration: September 2023-June 2024)

9) Mr. Bikram Das (IntPhD, SAIS, project duration: September 2023-June 2024)

10) Ms. Latanjali Maharana (IntPhD, SAIS, project duration: September 2023-June 2024)

11) Mr. Arpan Banerjee (BS-MS, project duration: September 2022-June 2024)

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Get in touch with us!

Lab No.: M-048, M-052, M-044, M-154B

School of Applied and Interdisciplinary Sciences, Indian Association for the Cultivation of science, 2A & 2B Raja S.C. Mullick Road, Kolkata - 700 032

+91-33-2473 4971 (Ext. 2128)

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© 2024 The Morpholino Group, IACS Kolkata

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